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CPCSEA GUIDELINES 2014 PDF

Guidelines regarding constitution / reconstitution of IAEC 48th Meeting of CPCSEA was held on 21st August, under the Chairmanship of Shri Hem. PDF | The effect of implementation of guidelines of the Committee for the Purpose of Control and The results showed that the implementation of CPCSEA guidelines in pharmacy institution . Mar ; J Indian Assoc Pediatr Surg. PDF | On Dec 29, , Pandey Govind and others published Guidelines of CPCSEA for conducting the experiment on animals.

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Animal use in pharmacology education and research: The changing scenario

Cell culture is a promising alternative to animal use. BBC news; [Last accessed on May 30]. As xpcsea advances, these alternatives, especially in vitro and in silico techniques would receive wide acceptance by researchers and regulatory bodies, as well.

However, the animal use and their handling vary in each laboratory and educational institution. An overview with special reference to Indian context. Primary uses of animals in experimentation Education Until some years ago, it was a common sight to see a hapless frog jumping under a pithing needle.

Nearlyfish and 20, amphibians were used in the UK inpredominantly zebra fish, Danio rerio and the African clawed frog, Xenopus laevis. This preclinical safety and efficacy data is needed for submission to drug regulatory authorities before the permission for further studies in humans are granted. So how do we judge the ethical issues in animal experimentation? There is a belief that just as medicine cannot be taught or learnt without exposure to wards and clinics, pharmacology cannot be taught without experimentation in animals.

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Replacement methods can be absolute guiidelines i. Guidelines for use of laboratory animals in medical colleges. In this review, we discuss the evolution of the use of animals in education and research and how these have been affected in recent times owing to concerns from animal lovers and government regulations.

A number of tests are performed, lasting less than a month to years to test general toxicity, eye and skin irritancy, mutagenicity, carcinogenicity and teratogenicity. In Silico Computer based The in silico methods include models of diabetes, asthma and drug absorption. While experiments of vertebrates are regulated in most countries, those on invertebrates are not, and hence their accurate usage statistics are lacking.

Multi-platform E-Cell simulation system. Student evaluation of teaching and assessment methods in pharmacology.

Animal use in pharmacology education and research: The changing scenario

There have been threats to researchers from animal rights activists. National Center for Biotechnology InformationU. Limulus ameobocyte lysate assay and human whole blood pyrogen test have replaced rabbit pyrogen tests. Rabbits are also frequently used for production of polyclonal antibodies. Opportunities to avoid redundant testing and use alternative approaches. Until some years ago, it was a common sight to see a hapless frog jumping under a pithing needle.

Invertebrates can be used to replace the more commonly used laboratory animals. Validation, regulatory acceptance and international harmonization. It can predict drug interactions much before a drug is marketed.

On the other hand, animal activists were using extreme measures to stop animal use. Typical experiments included effect of drugs on rabbit intestine, rabbit eye, central nervous system, reproductive system, as also the frog heart and frog rectus. Substitute of animals in drug research: Table of validated and accepted alternative methods updated [Last accessed on May 30].

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They must not only initiate and encourage the projects for the development of alternatives in education but also ensure their implementation, by providing the requisite infrastructure in all institutions.

Home :Committee for the Purpose of Control And Supervision of Experiments on Animals

The MCI amendment in asked all medical colleges to use alternatives to animal experiments in the undergraduate medical course. The sources also vary based on species required. Several students objected openly against animal dissection exercises thereafter. Where is the evidence that animal research benefits humans?

The dilemma to continue animal experiments in education and research continues with varied and confusing guidelines. Recommendation for import of animals for use in experiments. Early modern experimentation on live animals. Introduction The mission of medicine is to eliminate suffering to maintain a good health, which may prolong the life. The guidelinee protection movement was started in 18 th century by a group of people known as abolitionists in England.

Computer-based alternatives were used to some extent by all countries. Badyal and Chetna Desai 1. Regulations on graduate medical education, amended upto Journal List Indian J Pharmacol v. The debate surrounding animal use in experiments and teaching started way back in the 17 th century.